| Gene | Family ID # | Chromosome | Chromosome Region* (NCBI Build 34) |
Status | Post Date | |
| Flanking Markers | Base Pair | |||||
| repro19 | G1-472-18 | Chr 16 | D16Mit165 to D16Mit103 | 12732404-30793475 | Cryopreserved | 1/18/05 |
| Male Phenotype |
In vitro clinic: Low testis weight, low seminal vesicle weight, low epididymal sperm concentration, abnormally shaped sperm heads with missing or short sperm tails, variable motility, very low IVF success. Histology evaluation: Abnormal spermatogenesis (see 1-3) with low/abnormal spermatogonia and spermatocytes. Abnormal spermiogenesis with abnormal spermatid heads (see 2), low number of spermatids in testis lumen (see 3). Hormone analysis: High levels of luteinizing hormone and testosterone. |
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Instructions for viewing candidate genes for this mutant line
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| 1. Abnormal spermatogenesis | 2. Spermatocyte and spermatogonial cell depletion, abnormal spermatid heads | 3. Spermatocyte and spermatogonial cell depletion, low number of spermatids in lumen |
*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.
