Gene Family ID # Chromosome Chromosome Region*
(NCBI Build 34)
Status Post Date
Flanking Markers Base Pair
repro57 G1-586-2 Chr 5 D5Mit312 to D5Mit68 95409878-118958939 Cryopreserved 5/14/07
Male
Phenotype

In vitro clinic: Very low testis weight, low seminal vesicle weight, no epididymal sperm recovered.

Histology evaluation: Arrest of spermatogenesis during late pachytene stage of meiotic prophase (see 1), some germ cells appear apoptotic (see 2).

Instructions for viewing candidate genes for this mutant line

Select the descriptive text below to view a larger image:

     
1. Arrest of germ cells  2. Apoptotic germ cells    
     
     

*The scope of our funding includes mapping of the mutation to a chromosomal region, but in most cases does not include cloning of the gene responsible for the infertile phenotype.