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The Trowbridge Lab

Researches regulation of stem cells in the blood in normal development, aging and leukemia transformation.

Our Research Focus

The Trowbridge laboratory researches the development and maintenance of hematopoietic stem cells (HSCs), as well as alterations that occur during normal aging and during transformation to leukemic cells. Our current focus is on the epigenetic regulation of these processes, with the goal of identifying biomarkers of disease that can be targeted for new therapies.

Principal Investigator

Jennifer Trowbridge, Ph.D.

Location

Bar Harbor, ME

Contact

207-288-6183

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Topics

Cancer Cell Line Xenograft Efficacy Studies, PDX Efficacy Services, PDX-Seq, Patient-Derived Acute Myeloid Leukemia (AML) Models, Patient-Derived Xenograft (PDX) Models, PDX Live™: Efficacy Studies on Demand, Onco-Hu® Mouse Models, Immuno-oncology, Preclinical Oncology Platforms​, Family History Pedigree Tool, Colorectal Cancer Resources, Preclinical Research Services, The JAX Cancer Center, Breeding Services, Comparing Genetic Tests, Management of Genetic Risk, Ethical Issues in Genetics, Clinical Education Resources, Hereditary Cancer Resources, Breast Cancer Resources, JAX® Mice & Services, Immune Humanized Mouse Models, Oncology Services Form, PDX Live™ Tumor Interest Form, Featured JAX® Mice for Cancer Research, Online Resources for Cancer Research, Solutions by Therapeutic Area, Mouse Biospecimens, NSG™ Variants Portfolio, Find Lab Mice, Most Popular JAX Mice Strains, Minute to Understanding: What are telomeres?, Say goodbye to one-size-fits-all cancer treatments, Cancer Research Training and Education Coordination, JAX Cancer Center Membership Resources, Hereditary Breast and Ovarian Cancer Syndrome, Communicating with Family, Genetically Related Cancers, Case: Variant of Uncertain Significance, Case: Identify patients for germline testing, Why JAX® Mice?, Cancer, Membership, JAX Cancer Research News, JAX Cancer Center Yearly Highlights, Genetic Testing Results Interpretation Tool, Lynch Syndrome Factsheet, Familial Adenomatous Polyposis, Components of a Cancer Genetic Counseling Session, Communicating Genetic Risk, Three things to know about direct-to-consumer breast cancer genetic testing, Hereditary Cancer Management Guidelines, Cancer Genetic Risk Assessment, Customer Support, JAX Center for Aging Research, Minute to Understanding: What is epigenetics?, Aging Service Project Quote, Aged C57BL/6J Mice, CD34+ Humanized NSG-FLT3 Mice, Minute to Understanding: Lifespan vs. healthspan, Could 100 be the new 50?

Lab Staff

Leading the search for tomorrow's cures

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